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The S190R mutation in the hemagglutinin protein of pandemic H1N1 2009 influenza virus increased its pathogenicity in mice.
Chen, Yongkun; Bai, Tian; Zhu, Wenfei; Gao, Rongbao; Deng, Zhihong; Shi, Yi; Zou, Shumei; Huang, Yiwei; Li, Xiyan; Li, Fangcai; Feng, Zhaomin; Chen, Tao; Yang, Jing; Wang, Dayan; Gao, Lidong; Shu, Yuelong.
Afiliação
  • Chen Y; National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
  • Bai T; Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, 102206, China.
  • Zhu W; National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
  • Gao R; Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, 102206, China.
  • Deng Z; National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
  • Shi Y; Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, 102206, China.
  • Zou S; National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
  • Huang Y; Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, 102206, China.
  • Li X; Hunan Provincial Center for Disease Control and Prevention, Changsha, 410005, China.
  • Li F; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.
  • Feng Z; National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
  • Chen T; Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, 102206, China.
  • Yang J; Hunan Provincial Center for Disease Control and Prevention, Changsha, 410005, China.
  • Wang D; National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
  • Gao L; Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, 102206, China.
  • Shu Y; Hunan Provincial Center for Disease Control and Prevention, Changsha, 410005, China.
Sci China Life Sci ; 61(7): 836-843, 2018 07.
Article em En | MEDLINE | ID: mdl-29445999

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Virais / Infecções por Orthomyxoviridae / Glicoproteínas de Hemaglutininação de Vírus da Influenza / Vírus da Influenza A Subtipo H1N1 / Mutação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci China Life Sci Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Virais / Infecções por Orthomyxoviridae / Glicoproteínas de Hemaglutininação de Vírus da Influenza / Vírus da Influenza A Subtipo H1N1 / Mutação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci China Life Sci Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China