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Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease.
Zhou, Xiao; Li, Gang; Kaplan, Anna; Gaschler, Michael M; Zhang, Xiaoyan; Hou, Zhipeng; Jiang, Mali; Zott, Roseann; Cremers, Serge; Stockwell, Brent R; Duan, Wenzhen.
Afiliação
  • Zhou X; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Li G; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Kaplan A; Department of Pharmacology, Pharmacy School, Inner Mongolian Medical University, Hohhot, Inner Mongolian, 010110, China.
  • Gaschler MM; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Zhang X; Department of Chemistry, Columbia University, New York, NY 10027, USA.
  • Hou Z; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Jiang M; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Zott R; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Cremers S; Irving Institute for Clinical and Translational Research, Columbia University Medical Center, New York, NY 10027, USA.
  • Stockwell BR; Irving Institute for Clinical and Translational Research, Columbia University Medical Center, New York, NY 10027, USA.
  • Duan W; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10027, USA.
Hum Mol Genet ; 27(9): 1545-1555, 2018 05 01.
Article em En | MEDLINE | ID: mdl-29462355
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Huntington / Isomerases de Dissulfetos de Proteínas / Proteína Huntingtina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Huntington / Isomerases de Dissulfetos de Proteínas / Proteína Huntingtina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos