Reproductive toxicology of disinfection by-products.
Environ Health Perspect
; 69: 177-82, 1986 Nov.
Article
em En
| MEDLINE
| ID: mdl-2949968
ABSTRACT
The chronic exposure of large segments of the population to disinfected drinking water has necessitated an evaluation of the health effects of the by-products of the chlorination process. This paper reviews the available information concerning the reproductive consequences associated with exposure to disinfection by-products. Four groups of compounds are discussed the trihalomethanes, in particular chloroform; the chlorinated phenols; chlorinated humic substances; and the haloacetonitriles. In the pregnant female, chloroform and the 2- and 2,4-chlorophenols produced low levels of embryo- and fetotoxicity. Chloroform induced terata when administered by inhalation. The chlorinated humic substances and 2,4,6-trichlorophenol were without significant reproductive effects. The haloacetonitriles showed in utero toxicity, becoming more severe with increasing halogen substitution.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reprodução
/
Abastecimento de Água
/
Desinfetantes
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Environ Health Perspect
Ano de publicação:
1986
Tipo de documento:
Article