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The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.
Daniel, Bence; Nagy, Gergely; Horvath, Attila; Czimmerer, Zsolt; Cuaranta-Monroy, Ixchelt; Poliska, Szilard; Hays, Tristan T; Sauer, Sascha; Francois-Deleuze, Jean; Nagy, Laszlo.
Afiliação
  • Daniel B; Sanford-Burnham-Prebys Medical Discovery Institute, Orlando, FL, USA.
  • Nagy G; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Horvath A; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Czimmerer Z; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Cuaranta-Monroy I; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Poliska S; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Hays TT; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Sauer S; Sanford-Burnham-Prebys Medical Discovery Institute, Orlando, FL, USA.
  • Francois-Deleuze J; Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Berlin, Germany.
  • Nagy L; CU Systems Medicine, University of Würzburg, Würzburg, Germany.
Nucleic Acids Res ; 46(9): 4425-4439, 2018 05 18.
Article em En | MEDLINE | ID: mdl-29506156

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-4 / PPAR gama / Receptores X de Retinoides / Fator de Transcrição STAT6 / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-4 / PPAR gama / Receptores X de Retinoides / Fator de Transcrição STAT6 / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos