Immune response and protective effect against chronic Toxoplasma gondii infection induced by vaccination with a DNA vaccine encoding profilin.

Gao, Qi; Zhang, Nian-Zhang; Zhang, Fu-Kai; Wang, Meng; Hu, Ling-Ying; Zhu, Xing-Quan

Gao, Qi; Zhang, Nian-Zhang; Zhang, Fu-Kai; Wang, Meng; Hu, Ling-Ying; Zhu, Xing-Quan.

Afiliação

Gao Q; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.
Zhang NZ; Hunan Entry-exit Inspection and Quarantine Bureau, Changsha, Hunan Province, 410004, People's Republic of China.
Zhang FK; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China. nianzhang919@163.com.
Wang M; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.
Hu LY; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.
Zhu XQ; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.

BMC Infect Dis ; 18(1): 117, 2018 03 07.

Article em En | MEDLINE | ID: mdl-29514647

Assuntos

Profilinas/genética; Proteínas de Protozoários/genética; Vacinas Protozoárias/imunologia; Toxoplasma/imunologia; Toxoplasmose/prevenção & controle; Vacinas de DNA/imunologia; Animais; Anticorpos Antiprotozoários/sangue; Citocinas/análise; Ensaio de Imunoadsorção Enzimática; Feminino; Imunidade Celular; Imunoglobulina G/sangue; Imunoglobulina G/classificação; Injeções Intramusculares; Interleucina-15/genética; Camundongos; Plasmídeos/genética; Plasmídeos/metabolismo; Linfócitos T/classificação; Linfócitos T/citologia; Linfócitos T/metabolismo; Toxoplasmose/imunologia; Vacinas de DNA/genética

Palavras-chave

Chronic toxoplasmosis; DNA vaccine; Immunogenicity; Profilin; Toxoplasma gondii

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Toxoplasma / Proteínas de Protozoários / Toxoplasmose / Vacinas Protozoárias / Vacinas de DNA / Profilinas Limite: Animals Idioma: En Revista: BMC Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2018 Tipo de documento: Article

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