Formation of COPI-coated vesicles at a glance.
J Cell Sci
; 131(5)2018 03 13.
Article
em En
| MEDLINE
| ID: mdl-29535154
ABSTRACT
The coat protein complex I (COPI) allows the precise sorting of lipids and proteins between Golgi cisternae and retrieval from the Golgi to the ER. This essential role maintains the identity of the early secretory pathway and impinges on key cellular processes, such as protein quality control. In this Cell Science at a Glance and accompanying poster, we illustrate the different stages of COPI-coated vesicle formation and revisit decades of research in the context of recent advances in the elucidation of COPI coat structure. By calling attention to an array of questions that have remained unresolved, this review attempts to refocus the perspectives of the field.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complexo I de Proteína do Envoltório
/
Vesículas Revestidas pelo Complexo de Proteína do Envoltório
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Retículo Endoplasmático
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Complexo de Golgi
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Cell Sci
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Alemanha