Pilot study to evaluate a new regimen to treat climacteric complaints with cyclic combined oestradiol valerate/medroxyprogesterone acetate.
Maturitas
; 9(1): 103-7, 1987 Apr.
Article
em En
| MEDLINE
| ID: mdl-2955203
Nineteen post-menopausal women suffering from climacteric complaints were treated with a cyclic regimen comprising 25 days on 2 mg oestradiol valerate and 5 mg medroxyprogesterone acetate daily, followed by a 5-day treatment-free interval. The mean duration of treatment was 20.2 mth. Control of bleeding was good; 9 women had slight monthly bleeding, 8 no bleeding at all, and 2 had only irregular spotting during the follow-up period. An endometrial biopsy was taken in 9 women in whom the mean duration of treatment was 30 mth. All endometrial biopsies showed an atrophic endometrium. A larger, randomized comparative study is now planned.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Climatério
/
Menopausa
/
Estradiol
/
Medroxiprogesterona
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Maturitas
Ano de publicação:
1987
Tipo de documento:
Article