Recognition and Conformational Properties of an Alternative Antithrombin Binding Sequence Obtained by Chemoenzymatic Synthesis.

Stancanelli, Eduardo; Elli, Stefano; Hsieh, Po-Hung; Liu, Jian; Guerrini, Marco

Stancanelli, Eduardo; Elli, Stefano; Hsieh, Po-Hung; Liu, Jian; Guerrini, Marco.

Afiliação

Stancanelli E; Department NMR and Carbohydrates, Istituto di Ricerche Chimiche e Biochimiche "G. Ronzoni", via G. Colombo 81, 20133, Milan, Italy.
Elli S; Department NMR and Carbohydrates, Istituto di Ricerche Chimiche e Biochimiche "G. Ronzoni", via G. Colombo 81, 20133, Milan, Italy.
Hsieh PH; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.
Liu J; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.
Guerrini M; Department NMR and Carbohydrates, Istituto di Ricerche Chimiche e Biochimiche "G. Ronzoni", via G. Colombo 81, 20133, Milan, Italy.

Chembiochem ; 2018 Mar 24.

Article em En | MEDLINE | ID: mdl-29573524

Palavras-chave

NMR spectroscopy; anticoagulant drugs; antithrombin; conformation analysis; heparin; molecular dynamics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Chembiochem Assunto da revista: BIOQUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Itália

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