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Safety and Efficacy of Subcutaneous Cardioverter Defibrillator in Patients at High Risk of Sudden Cardiac Death - Primary Japanese Experience.
Sasaki, Shingo; Tomita, Hirofumi; Tsurugi, Takuo; Ishida, Yuji; Shoji, Yoshihiro; Nishizaki, Kimitaka; Kinjo, Takahiko; Endo, Tomohide; Nishizaki, Fumie; Hanada, Kenji; Sasaki, Kenichi; Horiuchi, Daisuke; Kimura, Masaomi; Higuma, Takumi; Okamatsu, Hideharu; Tanaka, Yasuaki; Koyama, Junjiroh; Okumura, Ken.
Afiliação
  • Sasaki S; Department of Advanced Management of Cardiac Arrhythmias, Hirosaki University Graduate School of Medicine.
  • Tomita H; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Tsurugi T; Advanced Arrhythmia Therapeutic Branch, Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center.
  • Ishida Y; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Shoji Y; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Nishizaki K; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Kinjo T; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Endo T; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Nishizaki F; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Hanada K; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Sasaki K; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Horiuchi D; Department of Advanced Management of Cardiac Arrhythmias, Hirosaki University Graduate School of Medicine.
  • Kimura M; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Higuma T; Department of Cardiology, Hirosaki University Graduate School of Medicine.
  • Okamatsu H; Advanced Arrhythmia Therapeutic Branch, Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center.
  • Tanaka Y; Advanced Arrhythmia Therapeutic Branch, Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center.
  • Koyama J; Advanced Arrhythmia Therapeutic Branch, Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center.
  • Okumura K; Advanced Arrhythmia Therapeutic Branch, Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center.
Circ J ; 82(6): 1546-1551, 2018 05 25.
Article em En | MEDLINE | ID: mdl-29643282
ABSTRACT

BACKGROUND:

The entirely subcutaneous implantable cardioverter defibrillator (S-ICD) was introduced as a new alternative to conventional transvenous ICD (TV-ICD) in Japan in February 2016, but its safety and efficacy are unclear.Methods and 

Results:

A total of 60 patients (48 men, median age, 60 years; IQR, 44-67 years; primary prevention, n=24) underwent S-ICD implantation between February 2016 and August 2017. The device pocket was formed in the intermuscular space between the serratus anterior muscle and the latissimus dorsi muscle, and the parasternal S-ICD lead was placed according to pre-implant screening. Defibrillation test was performed in 56 patients (93%). Ventricular fibrillation (VF) was induced in 55 patients and terminated by a single 65-J shock in all patients. The median time to shock therapy was 13.4 s (IQR, 12.1-14.9 s) and the median post-shock impedance of the S-ICD lead was 64 Ω (IQR, 58-77 Ω). There were no operation-related complications or subsequent infectious complications. During follow-up (median, 275 days; IQR, 107-421 days), 1 patient (1.7%) had appropriate shock for VF with successful termination, whereas 5 patients (8.3%) had inappropriate shock due to oversensing of myopotential (n=3) or T-wave (n=1), and detection of supraventricular tachycardia (n=1).

CONCLUSIONS:

S-ICD is a safe and effective alternative to conventional TV-ICD. The long-term safety and efficacy of the S-ICD need further investigation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrilação Ventricular / Morte Súbita Cardíaca / Desfibriladores Implantáveis Tipo de estudo: Diagnostic_studies / Etiology_studies / Evaluation_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Circ J Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrilação Ventricular / Morte Súbita Cardíaca / Desfibriladores Implantáveis Tipo de estudo: Diagnostic_studies / Etiology_studies / Evaluation_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Circ J Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2018 Tipo de documento: Article