Shared effects of DISC1 disruption and elevated WNT signaling in human cerebral organoids.

Srikanth, Priya; Lagomarsino, Valentina N; Muratore, Christina R; Ryu, Steven C; He, Amy; Taylor, Walter M; Zhou, Constance; Arellano, Marlise; Young-Pearse, Tracy L

Srikanth, Priya; Lagomarsino, Valentina N; Muratore, Christina R; Ryu, Steven C; He, Amy; Taylor, Walter M; Zhou, Constance; Arellano, Marlise; Young-Pearse, Tracy L.

Afiliação

Srikanth P; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Lagomarsino VN; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Muratore CR; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Ryu SC; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
He A; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Taylor WM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Zhou C; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Arellano M; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Young-Pearse TL; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. tyoung@rics.bwh.harvard.edu.

Transl Psychiatry ; 8(1): 77, 2018 04 12.

Article em En | MEDLINE | ID: mdl-29643329

Assuntos

Córtex Cerebral/crescimento & desenvolvimento; Córtex Cerebral/metabolismo; Proteínas do Tecido Nervoso/metabolismo; Via de Sinalização Wnt; Apoptose; Proliferação de Células; Córtex Cerebral/patologia; Expressão Gênica; Humanos; Células-Tronco Pluripotentes Induzidas/fisiologia; Proteínas do Tecido Nervoso/genética; Organoides/metabolismo; Organoides/patologia; Técnicas de Cultura de Tecidos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Via de Sinalização Wnt / Proteínas do Tecido Nervoso Limite: Humans Idioma: En Revista: Transl Psychiatry Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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