A Case of Neurotrophic Keratopathy Associated with Nasopharyngeal Carcinoma.
Case Rep Ophthalmol
; 9(1): 114-118, 2018.
Article
em En
| MEDLINE
| ID: mdl-29643792
ABSTRACT
PURPOSE:
To report a case of neurotrophic keratopathy associated with nasopharyngeal carcinoma. CASE REPORT A 59-year-old man who had been diagnosed with a nasopharyngeal carcinoma was referred to the authors because of visual disturbance and pain in his right eye. Slit-lamp examination revealed a corneal epithelial defect and corneal stromal edema surrounding the epithelial defect area in his right eye. Magnetic resonance imaging showed a mass in his cavernous sinus, which was identified as nasopharyngeal carcinoma (NPC). We diagnosed neurotrophic keratopathy associated with NPC and initiated treatment with preservative-free artificial tears, antibiotic eye drops, fibronectin, a therapeutic contact lens, and amniotic membrane transplantation. However, the persistent corneal epithelial defect was unresponsive to these treatments.CONCLUSION:
Neurotrophic keratopathy secondary to NPC is thought to be rare. We presented a case of neurotrophic keratopathy associated with cavernous sinus metastasis of an NPC. The development of new and more effective treatments for this refractory disease is anticipated.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Case Rep Ophthalmol
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Japão