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Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia.
Burns, Melissa A; Liao, Zi Wei; Yamagata, Natsuko; Pouliot, Gayle P; Stevenson, Kristen E; Neuberg, Donna S; Thorner, Aaron R; Ducar, Matthew; Silverman, Emily A; Hunger, Stephen P; Loh, Mignon L; Winter, Stuart S; Dunsmore, Kimberly P; Wood, Brent; Devidas, Meenakshi; Harris, Marian H; Silverman, Lewis B; Sallan, Stephen E; Gutierrez, Alejandro.
Afiliação
  • Burns MA; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Liao ZW; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Yamagata N; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Pouliot GP; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Stevenson KE; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Neuberg DS; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Thorner AR; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Ducar M; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Silverman EA; Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Hunger SP; Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Loh ML; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Winter SS; Division of Oncology and the Center for Childhood Cancer Research, The Children's Hospital of Philadelphia and the Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Dunsmore KP; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94158, USA.
  • Wood B; Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM, 87131, USA.
  • Devidas M; Division of Oncology, University of Virginia Children's Hospital, Charlottesville, VA, 22903, USA.
  • Harris MH; Department of Laboratory Medicine, University of Washington, Seattle, 98195, WA, USA.
  • Silverman LB; Department of Biostatistics, University of Florida, Gainesville, FL, 32611, USA.
  • Sallan SE; Department of Pathology, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Gutierrez A; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.
Leukemia ; 32(10): 2126-2137, 2018 10.
Article em En | MEDLINE | ID: mdl-29654263
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Transformação Celular Neoplásica / Proteínas Hedgehog / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Carcinogênese / Mutação Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Animals / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Transformação Celular Neoplásica / Proteínas Hedgehog / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Carcinogênese / Mutação Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Animals / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos