Manipulating the expression of SARP family regulator BulZ and its target gene product to increase tacrolimus production.

Ma, Dongxu; Wang, Cheng; Chen, Hong; Wen, Jianping

Ma, Dongxu; Wang, Cheng; Chen, Hong; Wen, Jianping.

Afiliação

Ma D; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, 300072, People's Republic of China.
Wang C; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, People's Republic of China.
Chen H; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, 300072, People's Republic of China.
Wen J; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

Appl Microbiol Biotechnol ; 102(11): 4887-4900, 2018 Jun.

Article em En | MEDLINE | ID: mdl-29666890

Assuntos

Proteínas de Bactérias/biossíntese; Proteínas de Bactérias/genética; Regulação Bacteriana da Expressão Gênica; Streptomyces/genética; Tacrolimo/metabolismo; Tecnologia Farmacêutica/métodos; Fatores de Transcrição

Palavras-chave

SARP family transcriptional regulator; Streptomyces tsukubaensis; Tacrolimus; Target genes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptomyces / Proteínas de Bactérias / Regulação Bacteriana da Expressão Gênica / Tecnologia Farmacêutica / Tacrolimo Tipo de estudo: Prognostic_studies Idioma: En Revista: Appl Microbiol Biotechnol Ano de publicação: 2018 Tipo de documento: Article

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