The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth.

Heukers, Raimond; Fan, Tian Shu; de Wit, Raymond H; van Senten, Jeffrey R; De Groof, Timo W M; Bebelman, Maarten P; Lagerweij, Tonny; Vieira, Joao; de Munnik, Sabrina M; Smits-de Vries, Laura; van Offenbeek, Jody; Rahbar, Afsar; van Hoorick, Diane; Söderberg-Naucler, Cecilia; Würdinger, Thomas; Leurs, Rob; Siderius, Marco; Vischer, Henry F; Smit, Martine J

Heukers, Raimond; Fan, Tian Shu; de Wit, Raymond H; van Senten, Jeffrey R; De Groof, Timo W M; Bebelman, Maarten P; Lagerweij, Tonny; Vieira, Joao; de Munnik, Sabrina M; Smits-de Vries, Laura; van Offenbeek, Jody; Rahbar, Afsar; van Hoorick, Diane; Söderberg-Naucler, Cecilia; Würdinger, Thomas; Leurs, Rob; Siderius, Marco; Vischer, Henry F; Smit, Martine J.

Afiliação

Heukers R; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
Fan TS; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
de Wit RH; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
van Senten JR; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
De Groof TWM; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
Bebelman MP; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
Lagerweij T; Neuro-oncology Research Group, Cancer Center Amsterdam, VU University Medical Center, De Boelelaan 1117, Amsterdam, 1081 HV, The Netherlands.
Vieira J; Ablynx N.V., Technologiepark 21, Zwijnaarde, 9052, Belgium.
de Munnik SM; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
Smits-de Vries L; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
van Offenbeek J; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
Rahbar A; Department of Medicine Solna, Experimental Cardiovascular Research Unit and Department of Medicine and Neurology, Center for Molecular Medicine, Karolinska Institute, Stockholm, 171 77, Sweden.
van Hoorick D; Ablynx N.V., Technologiepark 21, Zwijnaarde, 9052, Belgium.
Söderberg-Naucler C; Department of Medicine Solna, Experimental Cardiovascular Research Unit and Department of Medicine and Neurology, Center for Molecular Medicine, Karolinska Institute, Stockholm, 171 77, Sweden.
Würdinger T; Neuro-oncology Research Group, Cancer Center Amsterdam, VU University Medical Center, De Boelelaan 1117, Amsterdam, 1081 HV, The Netherlands.
Leurs R; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
Siderius M; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
Vischer HF; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands.
Smit MJ; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1108, Amsterdam, 1081 HZ, The Netherlands. mj.smit@vu.nl.

Oncogene ; 37(30): 4110-4121, 2018 07.

Article em En | MEDLINE | ID: mdl-29706656

Assuntos

Neoplasias Encefálicas/genética; Proliferação de Células/genética; Citomegalovirus/genética; Glioblastoma/genética; Receptores de Quimiocinas/genética; Proteínas Virais/genética; Animais; Neoplasias Encefálicas/patologia; Células COS; Linhagem Celular; Chlorocebus aethiops; Feminino; Glioblastoma/patologia; Células HEK293; Humanos; Camundongos; Camundongos Nus; Células NIH 3T3; Receptores Virais/genética; Transdução de Sinais/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Neoplasias Encefálicas / Glioblastoma / Receptores de Quimiocinas / Citomegalovirus / Proliferação de Células Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda

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