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Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.
Pardi, Norbert; Hogan, Michael J; Naradikian, Martin S; Parkhouse, Kaela; Cain, Derek W; Jones, Letitia; Moody, M Anthony; Verkerke, Hans P; Myles, Arpita; Willis, Elinor; LaBranche, Celia C; Montefiori, David C; Lobby, Jenna L; Saunders, Kevin O; Liao, Hua-Xin; Korber, Bette T; Sutherland, Laura L; Scearce, Richard M; Hraber, Peter T; Tombácz, István; Muramatsu, Hiromi; Ni, Houping; Balikov, Daniel A; Li, Charles; Mui, Barbara L; Tam, Ying K; Krammer, Florian; Karikó, Katalin; Polacino, Patricia; Eisenlohr, Laurence C; Madden, Thomas D; Hope, Michael J; Lewis, Mark G; Lee, Kelly K; Hu, Shiu-Lok; Hensley, Scott E; Cancro, Michael P; Haynes, Barton F; Weissman, Drew.
Afiliação
  • Pardi N; Department of Medicine, University of Pennsylvania, Philadelphia, PA pnorbert@pennmedicine.upenn.edu.
  • Hogan MJ; Department of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Naradikian MS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
  • Parkhouse K; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Cain DW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.
  • Jones L; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.
  • Moody MA; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.
  • Verkerke HP; Department of Medicinal Chemistry, University of Washington, Seattle, WA.
  • Myles A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
  • Willis E; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, NC.
  • Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, NC.
  • Lobby JL; Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA.
  • Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.
  • Liao HX; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.
  • Korber BT; Los Alamos National Laboratory, Los Alamos, NM.
  • Sutherland LL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.
  • Scearce RM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.
  • Hraber PT; Los Alamos National Laboratory, Los Alamos, NM.
  • Tombácz I; Department of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Muramatsu H; Department of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Ni H; Department of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Balikov DA; Department of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Li C; Department of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Mui BL; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Tam YK; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Karikó K; BioNTech RNA Pharmaceuticals, Mainz, Germany.
  • Polacino P; Washington National Primate Research Center, University of Washington, Seattle, WA.
  • Eisenlohr LC; Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA.
  • Madden TD; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Hope MJ; Acuitas Therapeutics, Vancouver, BC, Canada.
  • Lewis MG; Bioqual Inc., Rockville, MD.
  • Lee KK; Department of Medicinal Chemistry, University of Washington, Seattle, WA.
  • Hu SL; Washington National Primate Research Center, University of Washington, Seattle, WA.
  • Hensley SE; Department of Pharmaceutics, University of Washington, Seattle, WA.
  • Cancro MP; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Haynes BF; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
  • Weissman D; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC.
J Exp Med ; 215(6): 1571-1588, 2018 06 04.
Article em En | MEDLINE | ID: mdl-29739835
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Linfócitos B / Linfócitos T Auxiliares-Indutores / Centro Germinativo / Vacinas de Subunidades Antigênicas / Nucleosídeos Limite: Animals Idioma: En Revista: J Exp Med Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Panamá
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Linfócitos B / Linfócitos T Auxiliares-Indutores / Centro Germinativo / Vacinas de Subunidades Antigênicas / Nucleosídeos Limite: Animals Idioma: En Revista: J Exp Med Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Panamá