Rapid LC-MS/MS method for quantification of vinorelbine and 4-O-deacetylvinorelbine in human whole blood suitable to monitoring oral metronomic anticancer therapy.

Corona, Giuseppe; Gusella, Milena; Gaspardo, Anna; Miolo, Gianmaria; Bertolaso, Laura; Pezzolo, Elisa; Pasini, Felice; Steffan, Agostino; Caruso, Donatella

Corona, Giuseppe; Gusella, Milena; Gaspardo, Anna; Miolo, Gianmaria; Bertolaso, Laura; Pezzolo, Elisa; Pasini, Felice; Steffan, Agostino; Caruso, Donatella.

Afiliação

Corona G; Immunopathology and Cancer Biomarkers Unit, Translational Research Department, IRCCS National Cancer Institute, Aviano, Italy.
Gusella M; Oncology Department, Santa Maria della Misericordia Hospital, Rovigo, Italy.
Gaspardo A; Pharmacological and Biomolecular Science Department, University of Milan Milan, Italy.
Miolo G; Medical and Preventive Oncology Unit, IRCCS National Cancer Institute, Aviano, Italy.
Bertolaso L; Oncology Department, Santa Maria della Misericordia Hospital, Rovigo, Italy.
Pezzolo E; Oncology Department, Santa Maria della Misericordia Hospital, Rovigo, Italy.
Pasini F; Medical Oncology Unit, Piero Pederzoli Hospital, Peschiera del Garda, Italy.
Steffan A; Immunopathology and Cancer Biomarkers Unit, Translational Research Department, IRCCS National Cancer Institute, Aviano, Italy.
Caruso D; Pharmacological and Biomolecular Science Department, University of Milan Milan, Italy.

Biomed Chromatogr ; : e4282, 2018 May 10.

Article em En | MEDLINE | ID: mdl-29749011

Palavras-chave

4-O-deacetylvinorelbine; LC/MS/MS; cancer; metronomic; vinorelbine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biomed Chromatogr Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Itália

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