A conserved human DJ1-subfamily motif (DJSM) is critical for anti-oxidative and deglycase activities of Plasmodium falciparum DJ1.

Nair, Divya N; Prasad, Rajesh; Singhal, Neha; Bhattacharjee, Manish; Sudhakar, Renu; Singh, Pushpa; Thanumalayan, Subramonian; Kiran, Uday; Sharma, Yogendra; Sijwali, Puran Singh

Nair, Divya N; Prasad, Rajesh; Singhal, Neha; Bhattacharjee, Manish; Sudhakar, Renu; Singh, Pushpa; Thanumalayan, Subramonian; Kiran, Uday; Sharma, Yogendra; Sijwali, Puran Singh.

Afiliação

Nair DN; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 500007, TS, India.
Prasad R; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 500007, TS, India.
Singhal N; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 500007, TS, India.
Bhattacharjee M; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 500007, TS, India.
Sudhakar R; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 500007, TS, India.
Singh P; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 500007, TS, India.
Thanumalayan S; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 500007, TS, India.
Kiran U; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 500007, TS, India.
Sharma Y; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 500007, TS, India.
Sijwali PS; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 500007, TS, India. Electronic address: psijwali@ccmb.res.in.

Mol Biochem Parasitol ; 222: 70-80, 2018 06.

Article em En | MEDLINE | ID: mdl-29753659

Assuntos

Estresse Oxidativo; Plasmodium falciparum/enzimologia; Plasmodium falciparum/metabolismo; Proteína Desglicase DJ-1/química; Proteína Desglicase DJ-1/metabolismo; Proteínas de Protozoários/química; Proteínas de Protozoários/metabolismo; Motivos de Aminoácidos; Sequência de Aminoácidos; Catálise; Sequência Conservada; Humanos; Plasmodium falciparum/química; Plasmodium falciparum/genética; Proteína Desglicase DJ-1/genética; Proteínas de Protozoários/genética; Alinhamento de Sequência

Palavras-chave

Anti-oxidative activity; DJ-1/ThiJ/PfpI; DJSM; Deglycase; PlasmoDJ1; hDJ1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Proteínas de Protozoários / Estresse Oxidativo / Proteína Desglicase DJ-1 Limite: Humans Idioma: En Revista: Mol Biochem Parasitol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Índia

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