Treatment of progressive multiple sclerosis: Challenges and promising perspectives.
Rev Neurol (Paris)
; 174(6): 441-448, 2018 Jun.
Article
em En
| MEDLINE
| ID: mdl-29779852
ABSTRACT
Management of progressive multiple sclerosis (MS) is one of the main challenges of the new century. Based on our knowledge of pathophysiology, three therapeutic strategies are proposed anti-inflammatory (ocrelizumab, siponimod
); remyelinating (opicinumab); and neuroprotective (high-dose biotin, ibudilast, simvastatin
). Nevertheless, despite recent promising positive clinical trials, new methodological approaches for therapeutic protocols with adaptable outcomes to assess progression are still needed.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esclerose Múltipla
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Revista:
Rev Neurol (Paris)
Ano de publicação:
2018
Tipo de documento:
Article