Amphiphilic Hybrid Dendritic-Linear Molecules as Nanocarriers for Shape-Dependent Antitumor Drug Delivery.

Guo, Yifei; Wang, Ting; Zhao, Shuang; Han, Meihua; Dong, Zhengqi; Wang, Xiangtao; Wang, Yanhong

Guo, Yifei; Wang, Ting; Zhao, Shuang; Han, Meihua; Dong, Zhengqi; Wang, Xiangtao; Wang, Yanhong.

Afiliação

Guo Y; Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , No. 151, Malianwa North Road , Haidian District, Beijing 100193 , China.
Wang T; Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , No. 151, Malianwa North Road , Haidian District, Beijing 100193 , China.
Zhao S; School of Pharmacy , Heilongjiang University of Chinese Medicine , No. 24, Heping Road , Xiangfang District, Harbin 150040 , China.
Han M; Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , No. 151, Malianwa North Road , Haidian District, Beijing 100193 , China.
Dong Z; Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , No. 151, Malianwa North Road , Haidian District, Beijing 100193 , China.
Wang X; Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , No. 151, Malianwa North Road , Haidian District, Beijing 100193 , China.
Wang Y; Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , No. 151, Malianwa North Road , Haidian District, Beijing 100193 , China.

Mol Pharm ; 15(7): 2665-2673, 2018 07 02.

Article em En | MEDLINE | ID: mdl-29782803

Assuntos

Antineoplásicos Fitogênicos/administração & dosagem; Camptotecina/análogos & derivados; Portadores de Fármacos/química; Neoplasias/tratamento farmacológico; Aminas/química; Animais; Antineoplásicos Fitogênicos/farmacocinética; Camptotecina/administração & dosagem; Camptotecina/farmacocinética; Linhagem Celular Tumoral/transplante; Modelos Animais de Doenças; Liberação Controlada de Fármacos; Ensaios de Seleção de Medicamentos Antitumorais; Humanos; Camundongos; Camundongos Endogâmicos BALB C; Nanosferas/química; Nanotubos/química; Neoplasias/patologia; Tamanho da Partícula; Polietilenoglicóis/química; Ratos; Tensoativos/química; Resultado do Tratamento

Palavras-chave

antitumor efficacy; dendritic linear molecules; self-assembly mechanism; shape-dependent property

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Camptotecina / Portadores de Fármacos / Neoplasias / Antineoplásicos Fitogênicos Limite: Animals / Humans Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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