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Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Kang, Yanyong; Kuybeda, Oleg; de Waal, Parker W; Mukherjee, Somnath; Van Eps, Ned; Dutka, Przemyslaw; Zhou, X Edward; Bartesaghi, Alberto; Erramilli, Satchal; Morizumi, Takefumi; Gu, Xin; Yin, Yanting; Liu, Ping; Jiang, Yi; Meng, Xing; Zhao, Gongpu; Melcher, Karsten; Ernst, Oliver P; Kossiakoff, Anthony A; Subramaniam, Sriram; Xu, H Eric.
Afiliação
  • Kang Y; Center for Cancer and Cell Biology, Innovation and Integration Program, Van Andel Research Institute, Grand Rapids, MI, USA.
  • Kuybeda O; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • de Waal PW; Center for Cancer and Cell Biology, Innovation and Integration Program, Van Andel Research Institute, Grand Rapids, MI, USA.
  • Mukherjee S; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, USA.
  • Van Eps N; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
  • Dutka P; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, USA.
  • Zhou XE; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
  • Bartesaghi A; Center for Cancer and Cell Biology, Innovation and Integration Program, Van Andel Research Institute, Grand Rapids, MI, USA.
  • Erramilli S; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Morizumi T; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, USA.
  • Gu X; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
  • Yin Y; Center for Cancer and Cell Biology, Innovation and Integration Program, Van Andel Research Institute, Grand Rapids, MI, USA.
  • Liu P; Center for Cancer and Cell Biology, Innovation and Integration Program, Van Andel Research Institute, Grand Rapids, MI, USA.
  • Jiang Y; University of Chinese Academy of Sciences, Beijing, China.
  • Meng X; Key Laboratory of Receptor Research, VARI-SIMM Center, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Zhao G; Key Laboratory of Receptor Research, VARI-SIMM Center, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Melcher K; David Van Andel Advanced Cryo-Electron Microscopy Suite, Van Andel Research Institute, Grand Rapids, MI, USA.
  • Ernst OP; David Van Andel Advanced Cryo-Electron Microscopy Suite, Van Andel Research Institute, Grand Rapids, MI, USA.
  • Kossiakoff AA; Center for Cancer and Cell Biology, Innovation and Integration Program, Van Andel Research Institute, Grand Rapids, MI, USA.
  • Subramaniam S; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
  • Xu HE; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Nature ; 558(7711): 553-558, 2018 06.
Article em En | MEDLINE | ID: mdl-29899450

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rodopsina / Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP / Microscopia Crioeletrônica Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rodopsina / Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP / Microscopia Crioeletrônica Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos