Pro: Steroids Can Be Withdrawn After Transplant in Recipients With Autoimmune Hepatitis.
Liver Transpl
; 24(8): 1109-1112, 2018 08.
Article
em En
| MEDLINE
| ID: mdl-29923302
Corticosteroids have been a mainstay of immunosuppression following liver transplantation. However, evolution in the field of transplant immunology has produced steroid-free options, resulting in most transplant centers weaning steroids after transplant within days to months-an evidence-based management decision. Patients with autoimmune hepatitis (AIH), however, receive corticosteroids prior to transplant. This raises the question of whether these patients should also be weaned from corticosteroids. In this review, we discuss the benefits of avoiding steroid use in this population of patients-an approach that not only avoids the adverse effects of corticosteroids but does so without risking graft failure from recurrent AIH or from acute cellular rejection.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Terapia de Imunossupressão
/
Transplante de Fígado
/
Hepatite Autoimune
/
Glucocorticoides
/
Rejeição de Enxerto
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Liver Transpl
Assunto da revista:
GASTROENTEROLOGIA
/
TRANSPLANTE
Ano de publicação:
2018
Tipo de documento:
Article