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Iterative Chemical Engineering of Vancomycin Leads to Novel Vancomycin Analogs With a High in Vitro Therapeutic Index.
Mishra, Nigam M; Stolarzewicz, Izabela; Cannaerts, David; Schuermans, Joris; Lavigne, Rob; Looz, Yannick; Landuyt, Bart; Schoofs, Liliane; Schols, Dominique; Paeshuyse, Jan; Hickenbotham, Peter; Clokie, Martha; Luyten, Walter; Van der Eycken, Erik V; Briers, Yves.
Afiliação
  • Mishra NM; Laboratory for Organic and Microwave-Assisted Chemistry, Department of Chemistry, KU Leuven, Leuven, Belgium.
  • Stolarzewicz I; Laboratory for Organic and Microwave-Assisted Chemistry, Department of Chemistry, KU Leuven, Leuven, Belgium.
  • Cannaerts D; Department of Chemistry, Warsaw University of Life Sciences, Warsaw, Poland.
  • Schuermans J; Laboratory for Organic and Microwave-Assisted Chemistry, Department of Chemistry, KU Leuven, Leuven, Belgium.
  • Lavigne R; Laboratory of Gene Technology, Department of Biosystems, KU Leuven, Leuven, Belgium.
  • Looz Y; Laboratory of Gene Technology, Department of Biosystems, KU Leuven, Leuven, Belgium.
  • Landuyt B; Laboratory of Functional Genomics and Proteomics, Department of Biology, KU Leuven, Leuven, Belgium.
  • Schoofs L; Laboratory of Functional Genomics and Proteomics, Department of Biology, KU Leuven, Leuven, Belgium.
  • Schols D; Laboratory of Functional Genomics and Proteomics, Department of Biology, KU Leuven, Leuven, Belgium.
  • Paeshuyse J; Laboratory of Virology and Chemotherapy, Rega Institute, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
  • Hickenbotham P; Laboratory for Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium.
  • Clokie M; Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom.
  • Luyten W; Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom.
  • Van der Eycken EV; Laboratory of Functional Genomics and Proteomics, Department of Biology, KU Leuven, Leuven, Belgium.
  • Briers Y; Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Front Microbiol ; 9: 1175, 2018.
Article em En | MEDLINE | ID: mdl-29930540

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Microbiol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Bélgica

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Microbiol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Bélgica