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A Fungal Protease Model to Interrogate Allergic Lung Immunity.
Morgan Knight, J; Li, Evan; Tung, Hui-Ying; Landers, Cameron; Wheeler, Jake; Kheradmand, Farrah; Corry, David B.
Afiliação
  • Morgan Knight J; Departments of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Li E; Departments of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Tung HY; Departments of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.
  • Landers C; Departments of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Wheeler J; Departments of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Kheradmand F; Departments of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Corry DB; Departments of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.
Methods Mol Biol ; 1799: 1-9, 2018.
Article em En | MEDLINE | ID: mdl-29956139
ABSTRACT
Allergic airway diseases (asthma and chronic rhinosinusitis) are among the most common of all human diseases in heavily industrialized societies. Animal models of asthma have provided remarkable insight into allergic disease pathogenesis and will continue to drive the discovery of new therapeutic insights. We provide in this chapter a detailed protocol for inducing allergic immunity in the lungs of mice using a purified fungal protease and include related protocols for assessing immune endpoints.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Alérgenos / Fungos / Hipersensibilidade / Imunidade / Pulmão Tipo de estudo: Guideline Limite: Animals Idioma: En Revista: Methods Mol Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Alérgenos / Fungos / Hipersensibilidade / Imunidade / Pulmão Tipo de estudo: Guideline Limite: Animals Idioma: En Revista: Methods Mol Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos