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Efficacy of the MDM2 Inhibitor SAR405838 in Glioblastoma Is Limited by Poor Distribution Across the Blood-Brain Barrier.
Kim, Minjee; Ma, Daniel J; Calligaris, David; Zhang, Shuangling; Feathers, Ryan W; Vaubel, Rachael A; Meaux, Isabelle; Mladek, Ann C; Parrish, Karen E; Jin, Fang; Barriere, Cedric; Debussche, Laurent; Watters, James; Tian, Shulan; Decker, Paul A; Eckel-Passow, Jeanette E; Kitange, Gaspar J; Johnson, Aaron J; Parney, Ian F; Anastasiadis, Panos Z; Agar, Nathalie Y R; Elmquist, William F; Sarkaria, Jann N.
Afiliação
  • Kim M; University of Minnesota, Minneapolis, Minnesota.
  • Ma DJ; Mayo Clinic, Rochester, Minnesota.
  • Calligaris D; Brigham and Women's Hospital, Boston, Massachusetts.
  • Zhang S; Harvard Medical School, Boston, Massachusetts.
  • Feathers RW; University of Minnesota, Minneapolis, Minnesota.
  • Vaubel RA; Mayo Clinic, Jacksonville, Florida.
  • Meaux I; Mayo Clinic, Rochester, Minnesota.
  • Mladek AC; Sanofi Oncology, Vitry-sur-Seine, France.
  • Parrish KE; Mayo Clinic, Rochester, Minnesota.
  • Jin F; University of Minnesota, Minneapolis, Minnesota.
  • Barriere C; Mayo Clinic, Rochester, Minnesota.
  • Debussche L; Sanofi Oncology, Vitry-sur-Seine, France.
  • Watters J; Sanofi Oncology, Vitry-sur-Seine, France.
  • Tian S; Sanofi Oncology, Vitry-sur-Seine, France.
  • Decker PA; Mayo Clinic, Rochester, Minnesota.
  • Eckel-Passow JE; Mayo Clinic, Rochester, Minnesota.
  • Kitange GJ; Mayo Clinic, Rochester, Minnesota.
  • Johnson AJ; Mayo Clinic, Rochester, Minnesota.
  • Parney IF; Mayo Clinic, Rochester, Minnesota.
  • Anastasiadis PZ; Mayo Clinic, Rochester, Minnesota.
  • Agar NYR; Mayo Clinic, Jacksonville, Florida.
  • Elmquist WF; Brigham and Women's Hospital, Boston, Massachusetts.
  • Sarkaria JN; Harvard Medical School, Boston, Massachusetts.
Mol Cancer Ther ; 17(9): 1893-1901, 2018 09.
Article em En | MEDLINE | ID: mdl-29970480
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Espiro / Neoplasias Encefálicas / Barreira Hematoencefálica / Glioblastoma / Ensaios Antitumorais Modelo de Xenoenxerto / Proteínas Proto-Oncogênicas c-mdm2 / Indóis Limite: Animals / Female / Humans / Male Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Espiro / Neoplasias Encefálicas / Barreira Hematoencefálica / Glioblastoma / Ensaios Antitumorais Modelo de Xenoenxerto / Proteínas Proto-Oncogênicas c-mdm2 / Indóis Limite: Animals / Female / Humans / Male Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2018 Tipo de documento: Article