Your browser doesn't support javascript.
loading
Metagenomics analysis of the virome of 300 concentrates from a Swiss platelet bank.
Brito, Francisco; Cordey, Samuel; Delwart, Eric; Deng, Xutao; Tirefort, Diderik; Lemoine-Chaduc, Coralie; Zdobnov, Evgeny; Lecompte, Thomas; Kaiser, Laurent; Waldvogel-Abramowski, Sophie; Preynat-Seauve, Olivier.
Afiliação
  • Brito F; Department of Genetic Medicine and Development, Faculty of Medicine of Geneva, Geneva, Switzerland.
  • Cordey S; Swiss Institute of Bioinformatics, Geneva, Switzerland.
  • Delwart E; Laboratory of Virology, University Hospitals of Geneva, Geneva, Switzerland.
  • Deng X; Blood Systems Research Institute, San Francisco, CA, USA.
  • Tirefort D; Blood Systems Research Institute, San Francisco, CA, USA.
  • Lemoine-Chaduc C; Department of Internal Medicine of Medical Specialties, Faculty of Medicine of Geneva, Geneva, Switzerland.
  • Zdobnov E; Blood Transfusion Center, University Hospitals of Geneva, Geneva, Switzerland.
  • Lecompte T; Department of Genetic Medicine and Development, Faculty of Medicine of Geneva, Geneva, Switzerland.
  • Kaiser L; Swiss Institute of Bioinformatics, Geneva, Switzerland.
  • Waldvogel-Abramowski S; Department of Internal Medicine of Medical Specialties, Faculty of Medicine of Geneva, Geneva, Switzerland.
  • Preynat-Seauve O; Laboratory of Virology, University Hospitals of Geneva, Geneva, Switzerland.
Vox Sang ; 2018 Jul 18.
Article em En | MEDLINE | ID: mdl-30022500
ABSTRACT
BACKGROUND AND

OBJECTIVES:

Platelet concentrates are frequently transfused to patients with reduced immunity. An exhaustive description of their viral content is needed to prevent unwanted infection. MATERIAL AND

METHODS:

To track viral sequences, a shotgun metagenomics approach was used on a bank of 300 platelets concentrates. Sequences were analysed through the diagnostics-oriented pipeline ezVIR.

RESULTS:

We only observed viruses commonly described in healthy individuals.

CONCLUSION:

Herein is reported the first viral landscape of a platelet concentrates bank.
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Vox Sang Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Vox Sang Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça