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VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma.
Zhang, Jing; Wu, Tao; Simon, Jeremy; Takada, Mamoru; Saito, Ryoichi; Fan, Cheng; Liu, Xian-De; Jonasch, Eric; Xie, Ling; Chen, Xian; Yao, Xiaosai; Teh, Bin Tean; Tan, Patrick; Zheng, Xingnan; Li, Mingjie; Lawrence, Cortney; Fan, Jie; Geng, Jiang; Liu, Xijuan; Hu, Lianxin; Wang, Jun; Liao, Chengheng; Hong, Kai; Zurlo, Giada; Parker, Joel S; Auman, J Todd; Perou, Charles M; Rathmell, W Kimryn; Kim, William Y; Kirschner, Marc W; Kaelin, William G; Baldwin, Albert S; Zhang, Qing.
Afiliação
  • Zhang J; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Wu T; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Simon J; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Takada M; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Saito R; Department of Genetics, Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Fan C; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Liu XD; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Jonasch E; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Xie L; Departments of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Chen X; Departments of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Yao X; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Teh BT; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Tan P; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore.
  • Zheng X; Institute of Molecular and Cell Biology, Singapore 138673, Singapore.
  • Li M; Institute of Molecular and Cell Biology, Singapore 138673, Singapore.
  • Lawrence C; Laboratory of Cancer Epigenome, Department of Medical Sciences, National Cancer Centre, Singapore 169610, Singapore.
  • Fan J; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore 169857, Singapore.
  • Geng J; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore.
  • Liu X; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore 169857, Singapore.
  • Hu L; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Wang J; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Liao C; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Hong K; Department of Pathology, Huashan Hospital, Fudan University, Shanghai, China.
  • Zurlo G; Department of Urology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
  • Parker JS; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Auman JT; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Perou CM; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Rathmell WK; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Kim WY; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Kirschner MW; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Kaelin WG; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Baldwin AS; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Zhang Q; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Science ; 361(6399): 290-295, 2018 07 20.
Article em En | MEDLINE | ID: mdl-30026228

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oncogenes / Fatores de Transcrição / Carcinoma de Células Renais / Proteínas de Homeodomínio / Proteína Supressora de Tumor Von Hippel-Lindau / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Science Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oncogenes / Fatores de Transcrição / Carcinoma de Células Renais / Proteínas de Homeodomínio / Proteína Supressora de Tumor Von Hippel-Lindau / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Science Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos