Gluconeogenic precursor availability regulates flux through the glyoxylate shunt in <i>Pseudomonas aeruginosa</i>.

Crousilles, Audrey; Dolan, Stephen K; Brear, Paul; Chirgadze, Dimitri Y; Welch, Martin

Gluconeogenic precursor availability regulates flux through the glyoxylate shunt in Pseudomonas aeruginosa.

Crousilles, Audrey; Dolan, Stephen K; Brear, Paul; Chirgadze, Dimitri Y; Welch, Martin.

Afiliação

Crousilles A; From the Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, United Kingdom.
Dolan SK; From the Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, United Kingdom.
Brear P; From the Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, United Kingdom.
Chirgadze DY; From the Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, United Kingdom.
Welch M; From the Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, United Kingdom mw240@cam.ac.uk.

J Biol Chem ; 293(37): 14260-14269, 2018 09 14.

Article em En | MEDLINE | ID: mdl-30030382

Assuntos

Gluconeogênese; Glioxilatos/metabolismo; Isocitrato Liase/metabolismo; Pseudomonas aeruginosa/metabolismo; Acetilcoenzima A/metabolismo; Ciclo do Ácido Cítrico; Cristalografia por Raios X; Descarboxilação; Escherichia coli/metabolismo; Isocitrato Desidrogenase/antagonistas & inibidores; Isocitrato Desidrogenase/química; Isocitrato Desidrogenase/metabolismo; Isocitrato Liase/antagonistas & inibidores; Isocitrato Liase/química; Cinética; Ácido Oxaloacético/metabolismo; Fosforilação; Pseudomonas aeruginosa/enzimologia

Palavras-chave

Pseudomonas aeruginosa; acetyl coenzyme A (acetyl-CoA); allosteric regulation; bacterial metabolism; bacterial pathogenesis; bacterial virulence; enzyme regulation; enzyme structure; gluconeogenesis; glyoxylate shunt; isocitrate dehydrogenase; isocitrate lyase; metabolic adaptation; metabolic regulation; post-translational modification (PTM); tricarboxylic acid cycle (TCA cycle) (Krebs cycle)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Gluconeogênese / Glioxilatos / Isocitrato Liase Idioma: En Revista: J Biol Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

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