Multistep mutational transformation of a protein fold through structural intermediates.

Kumirov, Vlad K; Dykstra, Emily M; Hall, Branwen M; Anderson, William J; Szyszka, Taylor N; Cordes, Matthew H J

Kumirov, Vlad K; Dykstra, Emily M; Hall, Branwen M; Anderson, William J; Szyszka, Taylor N; Cordes, Matthew H J.

Afiliação

Kumirov VK; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, 85721-0088.
Dykstra EM; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, 85721-0088.
Hall BM; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, 85721-0088.
Anderson WJ; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, 85721-0088.
Szyszka TN; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, 85721-0088.
Cordes MHJ; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, 85721-0088.

Protein Sci ; 27(10): 1767-1779, 2018 10.

Article em En | MEDLINE | ID: mdl-30051937

Assuntos

Proteínas/química; Modelos Moleculares; Mutação; Ressonância Magnética Nuclear Biomolecular; Conformação Proteica; Dobramento de Proteína; Proteínas/genética

Palavras-chave

NMR spectroscopy; Structural evolution; chimera; folding specificity; hybrid sequence; metamorphic protein

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Tipo de estudo: Prognostic_studies Idioma: En Revista: Protein Sci Assunto da revista: BIOQUIMICA Ano de publicação: 2018 Tipo de documento: Article

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