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Antiviral Activity, Safety, and Pharmacokinetics of AL-794, a Novel Oral Influenza Endonuclease Inhibitor: Results of an Influenza Human Challenge Study.
Yogaratnam, Jeysen; Rito, Jennifer; Kakuda, Thomas N; Fennema, Hein; Gupta, Kusum; Jekle, C Andreas; Mitchell, Toni; Boyce, Malcolm; Sahgal, Omair; Balaratnam, Ganesh; Chanda, Sushmita; Van Remoortere, Pieter; Symons, Julian A; Fry, John.
Afiliação
  • Yogaratnam J; Alios Biopharma, part of Janssen Pharmaceutical Companies, South San Francisco, California.
  • Rito J; Alios Biopharma, part of Janssen Pharmaceutical Companies, South San Francisco, California.
  • Kakuda TN; Alios Biopharma, part of Janssen Pharmaceutical Companies, South San Francisco, California.
  • Fennema H; Janssen Research and Development, Beerse, Belgium.
  • Gupta K; Alios Biopharma, part of Janssen Pharmaceutical Companies, South San Francisco, California.
  • Jekle CA; Alios Biopharma, part of Janssen Pharmaceutical Companies, South San Francisco, California.
  • Mitchell T; Hammersmith Medicines Research, London, United Kingdom.
  • Boyce M; Hammersmith Medicines Research, London, United Kingdom.
  • Sahgal O; Hammersmith Medicines Research, London, United Kingdom.
  • Balaratnam G; hVIVO Services, Queen Mary BioEnterprises Innovation Centre, London, United Kingdom.
  • Chanda S; Alios Biopharma, part of Janssen Pharmaceutical Companies, South San Francisco, California.
  • Van Remoortere P; Janssen Research and Development, Titusville, New Jersey.
  • Symons JA; Alios Biopharma, part of Janssen Pharmaceutical Companies, South San Francisco, California.
  • Fry J; Alios Biopharma, part of Janssen Pharmaceutical Companies, South San Francisco, California.
J Infect Dis ; 219(2): 177-185, 2019 01 07.
Article em En | MEDLINE | ID: mdl-30053042
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Serina Endopeptidases / Endonucleases / Influenza Humana Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Infect Dis Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Serina Endopeptidases / Endonucleases / Influenza Humana Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Infect Dis Ano de publicação: 2019 Tipo de documento: Article