The Role of Dendritic Cells in the Differentiation of T Follicular Helper Cells.
J Immunol Res
; 2018: 7281453, 2018.
Article
em En
| MEDLINE
| ID: mdl-30057920
ABSTRACT
T follicular helper cells (TFH) are a subset of recently discovered CD4+ T cells. Their major function is to participate in the formation of germinal centres (GCs) and promote B cell proliferation and differentiation to play important roles in the production of antibodies. Currently, the functions of TFH cells are clear. However, the early differentiation of these cells is not clear. Dendritic cells (DCs) participate in the differentiation of TFH cells. Therefore, this article reviewed the research progress regarding the influence of DCs on the differentiation of TFH cells and their major underlying mechanisms.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células Dendríticas
/
Linfócitos B
/
Linfócitos T Auxiliares-Indutores
/
Centro Germinativo
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Immunol Res
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
China