Discovery of a Series of 3-Cinnoline Carboxamides as Orally Bioavailable, Highly Potent, and Selective ATM Inhibitors.

Barlaam, Bernard; Cadogan, Elaine; Campbell, Andrew; Colclough, Nicola; Dishington, Allan; Durant, Stephen; Goldberg, Kristin; Hassall, Lorraine A; Hughes, Gareth D; MacFaul, Philip A; McGuire, Thomas M; Pass, Martin; Patel, Anil; Pearson, Stuart; Petersen, Jens; Pike, Kurt G; Robb, Graeme; Stratton, Natalie; Xin, Guohong; Zhai, Baochang

Barlaam, Bernard; Cadogan, Elaine; Campbell, Andrew; Colclough, Nicola; Dishington, Allan; Durant, Stephen; Goldberg, Kristin; Hassall, Lorraine A; Hughes, Gareth D; MacFaul, Philip A; McGuire, Thomas M; Pass, Martin; Patel, Anil; Pearson, Stuart; Petersen, Jens; Pike, Kurt G; Robb, Graeme; Stratton, Natalie; Xin, Guohong; Zhai, Baochang.

Afiliação

Barlaam B; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Cadogan E; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Campbell A; Oncology, IMED Biotech Unit, AstraZeneca, Macclesfield, U.K.
Colclough N; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Dishington A; Oncology, IMED Biotech Unit, AstraZeneca, Macclesfield, U.K.
Durant S; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Goldberg K; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Hassall LA; Oncology, IMED Biotech Unit, AstraZeneca, Macclesfield, U.K.
Hughes GD; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
MacFaul PA; Oncology, IMED Biotech Unit, AstraZeneca, Macclesfield, U.K.
McGuire TM; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Pass M; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Patel A; Oncology, IMED Biotech Unit, AstraZeneca, Macclesfield, U.K.
Pearson S; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Petersen J; Discovery Sciences, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
Pike KG; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Robb G; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Stratton N; Discovery Sciences, IMED Biotech Unit, AstraZeneca, Cambridge, U.K.
Xin G; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing, P. R. China.
Zhai B; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing, P. R. China.

ACS Med Chem Lett ; 9(8): 809-814, 2018 Aug 09.

Article em En | MEDLINE | ID: mdl-30128072

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

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