[Rapid determination of 48 contaminant residues in food contact plastic products by ultra performance liquid chromatography-quadrupole/electrostatic field orbitrap high resolution mass spectrometry coupled with microwave-assisted extraction].
Se Pu
; 36(7): 634-642, 2018 Jul 08.
Article
em Zh
| MEDLINE
| ID: mdl-30136535
ABSTRACT
An ultra performance liquid chromatography-quadrupole/electrostatic field orbitrap high resolution mass spectrometry (UPLC-Q Orbitrap HRMS) method was developed for the rapid determination of 48 contaminant residues in food plastic packaging materials. The samples were extracted with methanol using microwave-assisted extraction. The separation of the 48 contaminants was performed on a CAPCELL PAK MG â
¡ C18 column (150 mm×2.0 mm, 5 µm) with gradient elution. Methanol (containing 0.04% (v/v) formic acid) and water (containing 0.04% (v/v) formic acid and 20 mmol/L ammonium acetate) were used as mobile phases. The compounds were detected under the full scan/date dependent-MS/MS (Full MS/dd-MS2) mode with a heated electrospray ionization (HESI) source. The calibration curves were linear with correlation coefficients no less than 0.9950. The limits of detection (LODs) ranged from 0.1 to 1.0 µg/kg. The average spiked recoveries of the 48 target compounds were between 71.2% and 108.8%, with relative standard derivations (RSDs) ranging from 2.2% to 11.8% (n=6). Compared to previous methods, this method has advantages of simpler sample preparation and higher sensitivity.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plásticos
/
Contaminação de Alimentos
/
Embalagem de Alimentos
Idioma:
Zh
Revista:
Se Pu
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
China