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Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection.
Zimmer, Bastian; Ewaleifoh, Osefame; Harschnitz, Oliver; Lee, Yoon-Seung; Peneau, Camille; McAlpine, Jessica L; Liu, Becky; Tchieu, Jason; Steinbeck, Julius A; Lafaille, Fabien; Volpi, Stefano; Notarangelo, Luigi D; Casanova, Jean-Laurent; Zhang, Shen-Ying; Smith, Gregory A; Studer, Lorenz.
Afiliação
  • Zimmer B; Center for Stem Cell Biology, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
  • Ewaleifoh O; Developmental Biology Program, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
  • Harschnitz O; Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Lee YS; Center for Stem Cell Biology, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
  • Peneau C; Developmental Biology Program, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
  • McAlpine JL; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065.
  • Liu B; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Necker Hospital for Sick Children, 75015 Paris, France.
  • Tchieu J; Imagine Institute, Paris Descartes University, 75015 Paris, France.
  • Steinbeck JA; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065.
  • Lafaille F; Center for Stem Cell Biology, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
  • Volpi S; Developmental Biology Program, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
  • Notarangelo LD; Center for Stem Cell Biology, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
  • Casanova JL; Developmental Biology Program, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
  • Zhang SY; Center for Stem Cell Biology, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
  • Smith GA; Developmental Biology Program, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
  • Studer L; Center for Stem Cell Biology, Sloan Kettering Institute for Cancer Research, New York, NY 10065.
Proc Natl Acad Sci U S A ; 115(37): E8775-E8782, 2018 09 11.
Article em En | MEDLINE | ID: mdl-30154162
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor 3 Toll-Like / Células-Tronco Pluripotentes Induzidas / Imunidade / Neurônios Limite: Child / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor 3 Toll-Like / Células-Tronco Pluripotentes Induzidas / Imunidade / Neurônios Limite: Child / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article