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Canine visceral hemangiosarcoma treated with surgery alone or surgery and doxorubicin: 37 cases (2005-2014).
Batschinski, Karen; Nobre, Alessandra; Vargas-Mendez, Ernesto; Tedardi, Marcello V; Cirillo, Juliana; Cestari, Greice; Ubukata, Rodrigo; Dagli, Maria Lucia Z.
Afiliação
  • Batschinski K; Av. Prof. Dr. Orlando Marques, 87 - Department of Pathology, Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science (Batschinski, Tedardi, Dagli), Av. Professor Lineu Prestes, 580 - Laboratory of Diet, Nutrition and Cancer, Faculty of Pharmaceutical Sci
  • Nobre A; Av. Prof. Dr. Orlando Marques, 87 - Department of Pathology, Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science (Batschinski, Tedardi, Dagli), Av. Professor Lineu Prestes, 580 - Laboratory of Diet, Nutrition and Cancer, Faculty of Pharmaceutical Sci
  • Vargas-Mendez E; Av. Prof. Dr. Orlando Marques, 87 - Department of Pathology, Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science (Batschinski, Tedardi, Dagli), Av. Professor Lineu Prestes, 580 - Laboratory of Diet, Nutrition and Cancer, Faculty of Pharmaceutical Sci
  • Tedardi MV; Av. Prof. Dr. Orlando Marques, 87 - Department of Pathology, Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science (Batschinski, Tedardi, Dagli), Av. Professor Lineu Prestes, 580 - Laboratory of Diet, Nutrition and Cancer, Faculty of Pharmaceutical Sci
  • Cirillo J; Av. Prof. Dr. Orlando Marques, 87 - Department of Pathology, Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science (Batschinski, Tedardi, Dagli), Av. Professor Lineu Prestes, 580 - Laboratory of Diet, Nutrition and Cancer, Faculty of Pharmaceutical Sci
  • Cestari G; Av. Prof. Dr. Orlando Marques, 87 - Department of Pathology, Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science (Batschinski, Tedardi, Dagli), Av. Professor Lineu Prestes, 580 - Laboratory of Diet, Nutrition and Cancer, Faculty of Pharmaceutical Sci
  • Ubukata R; Av. Prof. Dr. Orlando Marques, 87 - Department of Pathology, Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science (Batschinski, Tedardi, Dagli), Av. Professor Lineu Prestes, 580 - Laboratory of Diet, Nutrition and Cancer, Faculty of Pharmaceutical Sci
  • Dagli MLZ; Av. Prof. Dr. Orlando Marques, 87 - Department of Pathology, Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science (Batschinski, Tedardi, Dagli), Av. Professor Lineu Prestes, 580 - Laboratory of Diet, Nutrition and Cancer, Faculty of Pharmaceutical Sci
Can Vet J ; 59(9): 967-972, 2018 09.
Article em En | MEDLINE | ID: mdl-30197439
ABSTRACT
The purpose of this retrospective study was to determine survival times and prognostic factors of dogs with visceral hemangiosarcoma (HSA) treated with surgery alone or surgery and doxorubicin. Medical records from 2 hospitals from 2005 to 2014 were searched for dogs with histopathologically confirmed visceral HSA. Data relevant to patient demographics, tumor characteristics, and outcomes were abstracted. The most common primary organ affected was the spleen; however, primary tumor location had no influence on prognosis. Twenty-three dogs were treated with surgery alone, while 14 dogs were treated with surgery and doxorubicin. There was a significant difference in survival times between dogs treated with surgery alone and with surgery followed by doxorubicin (66 days versus 274 days). Dogs with stage I tumors (196 days) had a longer median survival time (MST) than dogs with stage II (117 days) and stage III (23 days) disease. The overall MST was 179 days with a 1-year survival rate of 29.2%.
Hémangiosarcome viscéral canin traité par la chirurgie seule et la doxorubicine 37 cas (2005­2014). Le but de cette étude rétrospective consistait à déterminer les temps de survie et les facteurs de pronostic des chiens atteints d'un hémangiosarcome (HSE) viscéral traités à l'aide de la chirurgie seule ou de la chirurgie et de la doxorubicine. Les dossiers médicaux de deux cliniques de 2005 à 2014 ont été fouillés pour trouver des chiens avec un HSE viscéral confirmé par histopathologie. Les données pertinentes pour les données démographiques du patient, les caractéristiques de la tumeur et les résultats ont été extraits des dossiers. L'organe primaire le plus couramment affecté était la rate. Cependant, l'emplacement primaire de la tumeur n'avait aucune influence sur le pronostic. Vingt-trois chiens ont été traités par la chirurgie seule, tandis que 14 chiens ont été traités par la chirurgie et la doxorubicine. Il y avait une différence importante dans les temps de survie entre les chiens traités par la chirurgie seule et la chirurgie suivie de la doxorubicine (66 jours contre 274 jours). Les chiens ayant des tumeurs de stade I (196 jours) avaient un temps de survie médian (TSM) plus long que les chiens atteints d'une maladie de stade II (117 jours) et de stade III (23 jours). Le TSM général était de 179 jours avec un taux de survie après 1 an de 29,2 %.(Traduit par Isabelle Vallières).
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doxorrubicina / Doenças do Cão / Hemangiossarcoma / Antineoplásicos Tipo de estudo: Observational_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Can Vet J Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doxorrubicina / Doenças do Cão / Hemangiossarcoma / Antineoplásicos Tipo de estudo: Observational_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Can Vet J Ano de publicação: 2018 Tipo de documento: Article