Catalyst-free synthesis of α-thioacrylic acids via cascade thiolation and 1,4-aryl migration of aryl alkynoates at room temperature.
Org Biomol Chem
; 16(37): 8379-8383, 2018 09 26.
Article
em En
| MEDLINE
| ID: mdl-30209456
ABSTRACT
A simple and facile catalyst-free method for the construction of α-thioacrylic acids has been developed from readily-available aryl alkynoates and thiols at room temperature. Various α-thioacrylic acids could be conveniently and efficiently obtained in moderate to good yields via cascade thiolation and 1,4-aryl migration of aryl alkynoates in the absence of any catalyst and additive.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Biomol Chem
Assunto da revista:
BIOQUIMICA
/
QUIMICA
Ano de publicação:
2018
Tipo de documento:
Article