Discovery of Potent Disheveled/Dvl Inhibitors Using Virtual Screening Optimized With NMR-Based Docking Performance Index.

Hori, Kiminori; Ajioka, Kasumi; Goda, Natsuko; Shindo, Asako; Takagishi, Maki; Tenno, Takeshi; Hiroaki, Hidekazu

Hori, Kiminori; Ajioka, Kasumi; Goda, Natsuko; Shindo, Asako; Takagishi, Maki; Tenno, Takeshi; Hiroaki, Hidekazu.

Afiliação

Hori K; Laboratory of Structural Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya, Japan.
Ajioka K; Department of Biological Science, School of Science, Nagoya University, Nagoya, Japan.
Goda N; Laboratory of Structural Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya, Japan.
Shindo A; Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya, Japan.
Takagishi M; Department of Pathology, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Tenno T; Laboratory of Structural Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya, Japan.
Hiroaki H; BeCellBar LLC, Business Incubation Center, Nagoya University, Nagoya, Japan.

Front Pharmacol ; 9: 983, 2018.

Article em En | MEDLINE | ID: mdl-30233369

Palavras-chave

NMR-derived docking performance index; Wnt signaling; proteinprotein interaction inhibitor; triple negative breast cancer; virtual screening

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Front Pharmacol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão

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