Functional and phylogenetic characterization of noncanonical vitamin B<sub>12</sub>-binding proteins in zebrafish suggests involvement in cobalamin transport.

Benoit, Courtney R; Stanton, Abigail E; Tartanian, Aileen C; Motzer, Andrew R; McGaughey, David M; Bond, Stephen R; Brody, Lawrence C

Functional and phylogenetic characterization of noncanonical vitamin B₁₂-binding proteins in zebrafish suggests involvement in cobalamin transport.

Benoit, Courtney R; Stanton, Abigail E; Tartanian, Aileen C; Motzer, Andrew R; McGaughey, David M; Bond, Stephen R; Brody, Lawrence C.

Afiliação

Benoit CR; From the Gene and Environment Interaction Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892 and.
Stanton AE; From the Gene and Environment Interaction Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892 and.
Tartanian AC; From the Gene and Environment Interaction Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892 and.
Motzer AR; From the Gene and Environment Interaction Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892 and.
McGaughey DM; From the Gene and Environment Interaction Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892 and.
Bond SR; Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892.
Brody LC; From the Gene and Environment Interaction Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892 and lbrody@mail.nih.gov.

J Biol Chem ; 293(45): 17606-17621, 2018 11 09.

Article em En | MEDLINE | ID: mdl-30237171

Assuntos

Transcobalaminas; Peixe-Zebra; Animais; Sistemas CRISPR-Cas; Domínios Proteicos; Transcobalaminas/química; Transcobalaminas/genética; Transcobalaminas/metabolismo; Vitamina B 12/química; Vitamina B 12/genética; Vitamina B 12/metabolismo; Peixe-Zebra/genética; Peixe-Zebra/metabolismo; Proteínas de Peixe-Zebra/química; Proteínas de Peixe-Zebra/genética; Proteínas de Peixe-Zebra/metabolismo

Palavras-chave

affinity; cobalamin; one-carbon metabolism; phylogenetics; protein evolution; transcobalamin; transport; vitamin B12; zebrafish

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peixe-Zebra / Transcobalaminas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2018 Tipo de documento: Article

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