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AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies.
Caenepeel, Sean; Brown, Sean P; Belmontes, Brian; Moody, Gordon; Keegan, Kathleen S; Chui, Danny; Whittington, Douglas A; Huang, Xin; Poppe, Leszek; Cheng, Alan C; Cardozo, Mario; Houze, Jonathan; Li, Yunxiao; Lucas, Brian; Paras, Nick A; Wang, Xianghong; Taygerly, Joshua P; Vimolratana, Marc; Zancanella, Manuel; Zhu, Liusheng; Cajulis, Elaina; Osgood, Tao; Sun, Jan; Damon, Leah; Egan, Regina K; Greninger, Patricia; McClanaghan, Joseph D; Gong, Jianan; Moujalled, Donia; Pomilio, Giovanna; Beltran, Pedro; Benes, Cyril H; Roberts, Andrew W; Huang, David C; Wei, Andrew; Canon, Jude; Coxon, Angela; Hughes, Paul E.
Afiliação
  • Caenepeel S; Oncology Research, Amgen Inc., Thousand Oaks, California.
  • Brown SP; Amgen Research, Amgen Inc., Thousand Oaks, California.
  • Belmontes B; Amgen Research, Amgen Inc., Thousand Oaks, California. phughes@amgen.com seanpomeroy@yahoo.com.
  • Moody G; Medicinal Chemistry, Amgen Inc., Thousand Oaks, California.
  • Keegan KS; Oncology Research, Amgen Inc., Thousand Oaks, California.
  • Chui D; Amgen Research, Amgen Inc., Thousand Oaks, California.
  • Whittington DA; Oncology Research, Amgen Inc., Thousand Oaks, California.
  • Huang X; Amgen Research, Amgen Inc., Thousand Oaks, California.
  • Poppe L; Oncology Research, Amgen Inc., Seattle, Washington.
  • Cheng AC; Amgen Research, Amgen Inc., Seattle, Washington.
  • Cardozo M; Amgen Research, Amgen Inc., Thousand Oaks, California.
  • Houze J; Genome Analysis Unit, Amgen Inc., Thousand Oaks, California.
  • Li Y; Molecular Engineering, Amgen Inc., Cambridge, Massachusetts.
  • Lucas B; Amgen Research, Amgen Inc., Cambridge, Massachusetts.
  • Paras NA; Molecular Engineering, Amgen Inc., Cambridge, Massachusetts.
  • Wang X; Amgen Research, Amgen Inc., Cambridge, Massachusetts.
  • Taygerly JP; Amgen Research, Amgen Inc., Thousand Oaks, California.
  • Vimolratana M; Discovery Attribute Sciences, Amgen Inc., Thousand Oaks, California.
  • Zancanella M; Molecular Engineering, Amgen Inc., South San Francisco, California.
  • Zhu L; Amgen Research, Amgen Inc., South San Francisco, California.
  • Cajulis E; Molecular Engineering, Amgen Inc., South San Francisco, California.
  • Osgood T; Amgen Research, Amgen Inc., South San Francisco, California.
  • Sun J; Amgen Research, Amgen Inc., Cambridge, Massachusetts.
  • Damon L; Medicinal Chemistry, Amgen Inc., Cambridge, Massachusetts.
  • Egan RK; Amgen Research, Amgen Inc., South San Francisco, California.
  • Greninger P; Medicinal Chemistry, Amgen Inc., South San Francisco, California.
  • McClanaghan JD; Amgen Research, Amgen Inc., South San Francisco, California.
  • Gong J; Medicinal Chemistry, Amgen Inc., South San Francisco, California.
  • Moujalled D; Amgen Research, Amgen Inc., South San Francisco, California.
  • Pomilio G; Medicinal Chemistry, Amgen Inc., South San Francisco, California.
  • Beltran P; Amgen Research, Amgen Inc., South San Francisco, California.
  • Benes CH; Medicinal Chemistry, Amgen Inc., South San Francisco, California.
  • Roberts AW; Amgen Research, Amgen Inc., South San Francisco, California.
  • Huang DC; Medicinal Chemistry, Amgen Inc., South San Francisco, California.
  • Wei A; Amgen Research, Amgen Inc., South San Francisco, California.
  • Canon J; Medicinal Chemistry, Amgen Inc., South San Francisco, California.
  • Coxon A; Amgen Research, Amgen Inc., South San Francisco, California.
  • Hughes PE; Medicinal Chemistry, Amgen Inc., South San Francisco, California.
Cancer Discov ; 8(12): 1582-1597, 2018 12.
Article em En | MEDLINE | ID: mdl-30254093
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cancer Discov Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cancer Discov Ano de publicação: 2018 Tipo de documento: Article