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On-chip spatiotemporal electrophysiological analysis of human stem cell derived cardiomyocytes enables quantitative assessment of proarrhythmia in drug development.
Asahi, Yumiko; Hamada, Tomoyo; Hattori, Akihiro; Matsuura, Kenji; Odaka, Masao; Nomura, Fumimasa; Kaneko, Tomoyuki; Abe, Yasuyuki; Takasuna, Kiyoshi; Sanbuissho, Atsushi; Yasuda, Kenji.
Afiliação
  • Asahi Y; Medicinal Safety Research Laboratories, Kasai R&D Center, Daiichi-Sankyo Co. Ltd., Edogawa, Tokyo, 134-8630, Japan.
  • Hamada T; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda, Tokyo, 101-0062, Japan.
  • Hattori A; Chiome Bioscience Inc. Shibuya, Tokyo, 151-0071, Japan.
  • Matsuura K; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda, Tokyo, 101-0062, Japan.
  • Odaka M; Organization for University Research Initiatives, Waseda University, 3-14-9 Ookubo, Shinjuku, Tokyo, 169-0072, Japan.
  • Nomura F; Waseda Bioscience Research Institute in Singapore (WABOIS), Helios, 11 Biopolis Way, 138667, Singapore.
  • Kaneko T; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda, Tokyo, 101-0062, Japan.
  • Abe Y; Organization for University Research Initiatives, Waseda University, 3-14-9 Ookubo, Shinjuku, Tokyo, 169-0072, Japan.
  • Takasuna K; Waseda Bioscience Research Institute in Singapore (WABOIS), Helios, 11 Biopolis Way, 138667, Singapore.
  • Sanbuissho A; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda, Tokyo, 101-0062, Japan.
  • Yasuda K; Organization for University Research Initiatives, Waseda University, 3-14-9 Ookubo, Shinjuku, Tokyo, 169-0072, Japan.
Sci Rep ; 8(1): 14536, 2018 09 28.
Article em En | MEDLINE | ID: mdl-30266924
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Miócitos Cardíacos / Avaliação Pré-Clínica de Medicamentos / Dispositivos Lab-On-A-Chip Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Miócitos Cardíacos / Avaliação Pré-Clínica de Medicamentos / Dispositivos Lab-On-A-Chip Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão