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Small-molecule AgrA inhibitors F12 and F19 act as antivirulence agents against Gram-positive pathogens.
Greenberg, Michael; Kuo, David; Jankowsky, Eckhard; Long, Lisa; Hager, Chris; Bandi, Kiran; Ma, Danyang; Manoharan, Divya; Shoham, Yaron; Harte, William; Ghannoum, Mahmoud A; Shoham, Menachem.
Afiliação
  • Greenberg M; Department of Biochemistrty, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
  • Kuo D; Department of Biochemistrty, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
  • Jankowsky E; Center for RNA and Therapeutics, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Long L; Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
  • Hager C; Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
  • Bandi K; Department of Biochemistrty, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
  • Ma D; University of Pittsburgh School of Medicine, Pittsburgh, USA.
  • Manoharan D; Department of Biochemistrty, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
  • Shoham Y; Department of Biochemistrty, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
  • Harte W; Q2 Pharma, Ltd., Haifa, Israel.
  • Ghannoum MA; Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Shoham M; Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Sci Rep ; 8(1): 14578, 2018 10 01.
Article em En | MEDLINE | ID: mdl-30275455
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Estafilocócicas / Proteínas de Bactérias / Transativadores / Fatores de Virulência / Bactérias Gram-Positivas / Antibacterianos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Estafilocócicas / Proteínas de Bactérias / Transativadores / Fatores de Virulência / Bactérias Gram-Positivas / Antibacterianos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos