Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial.

Stevic, Ines; Müller, Volkmar; Weber, Karsten; Fasching, Peter A; Karn, Thomas; Marmé, Frederic; Schem, Christian; Stickeler, Elmar; Denkert, Carsten; van Mackelenbergh, Marion; Salat, Christoph; Schneeweiss, Andreas; Pantel, Klaus; Loibl, Sibylle; Untch, Michael; Schwarzenbach, Heidi

Stevic, Ines; Müller, Volkmar; Weber, Karsten; Fasching, Peter A; Karn, Thomas; Marmé, Frederic; Schem, Christian; Stickeler, Elmar; Denkert, Carsten; van Mackelenbergh, Marion; Salat, Christoph; Schneeweiss, Andreas; Pantel, Klaus; Loibl, Sibylle; Untch, Michael; Schwarzenbach, Heidi.

Afiliação

Stevic I; Department of Tumor Biology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Müller V; Department of Gynecology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Weber K; GBG Forschungs GmbH, Neu-Isenburg, Germany.
Fasching PA; Department of Gynecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Karn T; University Women's Hospital, Frankfurt, Germany.
Marmé F; Center for Gynecological Oncology at University Women's Hospital, Heidelberg, Germany.
Schem C; Mammazentrum Hamburg, Hamburg, Germany.
Stickeler E; Universitätsklinikum Aachen, Aachen, Germany.
Denkert C; Charite Berlin, Institute of Pathology and German Cancer Consortium (DKTK), Partner Site, Berlin, Germany.
van Mackelenbergh M; Universitätsklinikums Schleswig-Holstein Kiel, Kiel, Germany.
Salat C; Hämatoonkologische Schwerpunktpraxis, Munich, Germany.
Schneeweiss A; Universitätsklinikum Heidelberg, Heidelberg, Germany.
Pantel K; Department of Tumor Biology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Loibl S; GBG Forschungs GmbH, Neu-Isenburg, Germany.
Untch M; Helios Kliniken Berlin-Buch, Berlin, Germany.
Schwarzenbach H; Department of Tumor Biology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany. h.schwarzenbach@uke.de.

BMC Med ; 16(1): 179, 2018 10 10.

Article em En | MEDLINE | ID: mdl-30301470

Assuntos

MicroRNAs/genética; Receptor ErbB-2/biossíntese; Neoplasias de Mama Triplo Negativas/tratamento farmacológico; Neoplasias de Mama Triplo Negativas/genética; Estudos de Casos e Controles; Estudos de Coortes; Exossomos; Feminino; Humanos; MicroRNAs/biossíntese; Pessoa de Meia-Idade; Terapia Neoadjuvante; Receptor ErbB-2/genética; Neoplasias de Mama Triplo Negativas/enzimologia; Neoplasias de Mama Triplo Negativas/patologia

Palavras-chave

Breast cancer; Exosomes; HER2-positive; MicroRNAs; Neoadjuvant therapy; Pathological complete response; Triple negative

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor ErbB-2 / MicroRNAs / Neoplasias de Mama Triplo Negativas Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Middle aged Idioma: En Revista: BMC Med Assunto da revista: MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha

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