Increased Bioavailable Berberine Protects Against Myocardial Ischemia Reperfusion Injury Through Attenuation of NF&#954;B and JNK Signaling Pathways.

Yu, Yang; Zhang, Ming; Hu, Yali; Zhao, Yali; Teng, Fei; Lv, Xiaoyan; Li, Ji; Zhang, Ying; Hatch, Grant M; Chen, Li

Increased Bioavailable Berberine Protects Against Myocardial Ischemia Reperfusion Injury Through Attenuation of NFκB and JNK Signaling Pathways.

Yu, Yang; Zhang, Ming; Hu, Yali; Zhao, Yali; Teng, Fei; Lv, Xiaoyan; Li, Ji; Zhang, Ying; Hatch, Grant M; Chen, Li.

Afiliação

Yu Y; Department of Pharmacology, College of Basic Medical Sciences, School of Nursing, Jilin University.
Zhang M; Department of Pharmacology, College of Basic Medical Sciences, School of Nursing, Jilin University.
Hu Y; Department of Pharmacology, College of Basic Medical Sciences, School of Nursing, Jilin University.
Zhao Y; Department of Pharmacology, College of Basic Medical Sciences, School of Nursing, Jilin University.
Teng F; Department of Pharmacology, College of Basic Medical Sciences, School of Nursing, Jilin University.
Lv X; Department of Pharmacology, College of Basic Medical Sciences, School of Nursing, Jilin University.
Li J; Department of Pharmacology, College of Basic Medical Sciences, School of Nursing, Jilin University.
Zhang Y; Department of Neurology and Neuroscience Center, First Hospital of Jilin University.
Hatch GM; Department of Pharmacology & Therapeutics, University of Manitoba, Manitoba Institute of Child Health.
Chen L; Department of Pharmacology, College of Basic Medical Sciences, School of Nursing, Jilin University.

Int Heart J ; 59(6): 1378-1388, 2018 Nov 28.

Article em En | MEDLINE | ID: mdl-30305576

Assuntos

Berberina/uso terapêutico; Cardiotônicos/uso terapêutico; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; Traumatismo por Reperfusão Miocárdica/prevenção & controle; NF-kappa B/metabolismo; Animais; Berberina/farmacocinética; Berberina/farmacologia; Disponibilidade Biológica; Biomarcadores/metabolismo; Cardiotônicos/farmacocinética; Cardiotônicos/farmacologia; Esquema de Medicação; Portadores de Fármacos; Interleucina-6/metabolismo; Masculino; Traumatismo por Reperfusão Miocárdica/metabolismo; Ratos; Ratos Wistar; Resultado do Tratamento; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

H9c2; Hypoxia/reoxygenation; Ischemia reperfusion heart injury; Solid dispersion of berberine with sodium caprate (HGSD)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Berberina / Cardiotônicos / Traumatismo por Reperfusão Miocárdica / NF-kappa B / Sistema de Sinalização das MAP Quinases Tipo de estudo: Evaluation_studies Limite: Animals Idioma: En Revista: Int Heart J Assunto da revista: CARDIOLOGIA Ano de publicação: 2018 Tipo de documento: Article

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