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Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing.
Liu, Cai; Zhang, Yifan; Chen, Weili; Lu, Youming; Li, Wei; Liu, Yongqiang; Lai, Xiaojuan; Gong, Yanchun; Liu, Xuefang; Li, Yongguo; Chen, Xiaoyan; Li, Xuening; Sun, Hongbin; Yang, Jin; Zhong, Dafang.
Afiliação
  • Liu C; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, China.
  • Zhang Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, China.
  • Chen W; Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
  • Lu Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, China.
  • Li W; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, China.
  • Liu Y; Jiangsu Vcare PharmaTech Co., Ltd., 15 Wanshou Road, Nanjing 211800, China.
  • Lai X; Jiangsu Vcare PharmaTech Co., Ltd., 15 Wanshou Road, Nanjing 211800, China.
  • Gong Y; Jiangsu Vcare PharmaTech Co., Ltd., 15 Wanshou Road, Nanjing 211800, China.
  • Liu X; Jiangsu Vcare PharmaTech Co., Ltd., 15 Wanshou Road, Nanjing 211800, China.
  • Li Y; Hua Medicine (Shanghai) Ltd., 275 Ai Di Sheng Road, Shanghai 201203, China.
  • Chen X; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, China.
  • Li X; Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai 200032, China. Electronic address: li.xuening@zs-hospital.sh.cn.
  • Sun H; State Key Laboratory of Natural Medicines and Center of Drug Discovery, College of Pharmacy, China Pharmaceutical University, 24 Tongjia Xiang, Nanjing 210009, China. Electronic address: hongbinsun@cpu.edu.cn.
  • Yang J; Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China. Electronic address: yjcpu@yahoo.com.
  • Zhong D; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, China. Electronic address: dfzhong@simm.ac.cn.
Eur J Pharm Sci ; 127: 151-160, 2019 Jan 15.
Article em En | MEDLINE | ID: mdl-30326264
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenilacetatos / Tiofenos / Inibidores da Agregação Plaquetária / Antagonistas do Receptor Purinérgico P2Y / Clopidogrel Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Humans Idioma: En Revista: Eur J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenilacetatos / Tiofenos / Inibidores da Agregação Plaquetária / Antagonistas do Receptor Purinérgico P2Y / Clopidogrel Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Humans Idioma: En Revista: Eur J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China