The Cost of Long Catalytic Loops in Folding and Stability of the ALS-Associated Protein SOD1.

Yang, Fan; Wang, Huabing; Logan, Derek T; Mu, Xin; Danielsson, Jens; Oliveberg, Mikael

Yang, Fan; Wang, Huabing; Logan, Derek T; Mu, Xin; Danielsson, Jens; Oliveberg, Mikael.

Afiliação

Yang F; Department of Biochemistry and Biophysics, Arrhenius Laboratories of Natural Sciences , Stockholm University , S-106 91 Stockholm , Sweden.
Wang H; Department of Biochemistry and Biophysics, Arrhenius Laboratories of Natural Sciences , Stockholm University , S-106 91 Stockholm , Sweden.
Logan DT; Division of Biochemistry & Structural Biology, Department of Chemistry , Lund University , Box 124, 22100 Lund , Sweden.
Mu X; Department of Biochemistry and Biophysics, Arrhenius Laboratories of Natural Sciences , Stockholm University , S-106 91 Stockholm , Sweden.
Danielsson J; Department of Biochemistry and Biophysics, Arrhenius Laboratories of Natural Sciences , Stockholm University , S-106 91 Stockholm , Sweden.
Oliveberg M; Department of Biochemistry and Biophysics, Arrhenius Laboratories of Natural Sciences , Stockholm University , S-106 91 Stockholm , Sweden.

J Am Chem Soc ; 140(48): 16570-16579, 2018 12 05.

Article em En | MEDLINE | ID: mdl-30359015

Assuntos

Superóxido Dismutase-1/química; Sequência de Aminoácidos; Biocatálise; Domínio Catalítico; Entropia; Humanos; Cinética; Mutação; Conformação Proteica; Dobramento de Proteína; Estabilidade Proteica; Superóxido Dismutase-1/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Superóxido Dismutase-1 Tipo de estudo: Health_economic_evaluation / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: J Am Chem Soc Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suécia

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