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Propionibacterium acnes induces discogenic low back pain via stimulating nucleus pulposus cells to secrete pro-algesic factor of IL-8/CINC-1 through TLR2-NF-κB p65 pathway.
Jiao, Yucheng; Yuan, Ye; Lin, Yazhou; Zhou, Zezhu; Zheng, Yuehuan; Wu, Wenjian; Tang, Guoqing; Chen, Yong; Xiao, Jiaqi; Li, Changwei; Chen, Zhe; Cao, Peng.
Afiliação
  • Jiao Y; Department of Orthopedics, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China.
  • Yuan Y; Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases with Integrated Chinese-Western Medicine, Shanghai Institute of Traumatology and Orthopedics, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China.
  • Lin Y; Department of Orthopedics, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China.
  • Zhou Z; Department of Orthopedics, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing, 102218, China.
  • Zheng Y; Department of Orthopedics, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China.
  • Wu W; Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases with Integrated Chinese-Western Medicine, Shanghai Institute of Traumatology and Orthopedics, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China.
  • Tang G; Department of Orthopedic Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, China.
  • Chen Y; Department of Orthopedics, Ruijin Hospital North, School of Medicine, Shanghai Jiaotong University, Shanghai, 201800, China.
  • Xiao J; Department of Orthopedics, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China.
  • Li C; Kunshan Hospital of Traditional Chinese medicine, Kunshan, 215300, China.
  • Chen Z; Kunshan Hospital of Traditional Chinese medicine, Kunshan, 215300, China.
  • Cao P; Department of Medical Microbiology and Parasitology, School of Medicine, Shanghai Jiaotong University, Shanghai, 200025, China.
J Mol Med (Berl) ; 97(1): 25-35, 2019 01.
Article em En | MEDLINE | ID: mdl-30397790
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propionibacterium acnes / Interleucina-8 / Infecções por Bactérias Gram-Positivas / Dor Lombar / Quimiocina CXCL1 / Degeneração do Disco Intervertebral Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Mol Med (Berl) Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propionibacterium acnes / Interleucina-8 / Infecções por Bactérias Gram-Positivas / Dor Lombar / Quimiocina CXCL1 / Degeneração do Disco Intervertebral Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Mol Med (Berl) Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China