Mutant p53-dependent mitochondrial metabolic alterations in a mesenchymal stem cell-based model of progressive malignancy.

Lonetto, Giuseppe; Koifman, Gabriela; Silberman, Alon; Attery, Ayush; Solomon, Hilla; Levin-Zaidman, Smadar; Goldfinger, Naomi; Porat, Ziv; Erez, Ayelet; Rotter, Varda

Lonetto, Giuseppe; Koifman, Gabriela; Silberman, Alon; Attery, Ayush; Solomon, Hilla; Levin-Zaidman, Smadar; Goldfinger, Naomi; Porat, Ziv; Erez, Ayelet; Rotter, Varda.

Afiliação

Lonetto G; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Koifman G; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Silberman A; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel.
Attery A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Solomon H; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Levin-Zaidman S; Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, 76100, Israel.
Goldfinger N; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Porat Z; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, 76100, Israel.
Erez A; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel.
Rotter V; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, 76100, Israel. varda.rotter@weizmann.ac.il.

Cell Death Differ ; 26(9): 1566-1581, 2019 09.

Article em En | MEDLINE | ID: mdl-30413783

Assuntos

Células-Tronco Mesenquimais/metabolismo; Mitocôndrias/metabolismo; Neoplasias/genética; Proteína Supressora de Tumor p53/genética; Animais; Carcinogênese/genética; Proliferação de Células/genética; Transformação Celular Neoplásica/genética; Modelos Animais de Doenças; Glicólise/genética; Humanos; Células-Tronco Mesenquimais/patologia; Metaboloma/genética; Camundongos; Mitocôndrias/genética; Proteínas Mutantes/genética; Proteínas Mutantes/metabolismo; Neoplasias/metabolismo; Neoplasias/patologia; Proteína Supressora de Tumor p53/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Células-Tronco Mesenquimais / Mitocôndrias / Neoplasias Tipo de estudo: Qualitative_research Limite: Animals / Humans Idioma: En Revista: Cell Death Differ Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Israel

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google