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PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer.
Ding, Liya; Kim, Hye-Jung; Wang, Qiwei; Kearns, Michael; Jiang, Tao; Ohlson, Carolynn E; Li, Ben B; Xie, Shaozhen; Liu, Joyce F; Stover, Elizabeth H; Howitt, Brooke E; Bronson, Roderick T; Lazo, Suzan; Roberts, Thomas M; Freeman, Gordon J; Konstantinopoulos, Panagiotis A; Matulonis, Ursula A; Zhao, Jean J.
Afiliação
  • Ding L; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Kim HJ; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Wang Q; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Kearns M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Jiang T; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Ohlson CE; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Li BB; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Xie S; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Liu JF; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Stover EH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Howitt BE; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Bronson RT; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Lazo S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Roberts TM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Konstantinopoulos PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address: panagiotis_konstantinopoulos@dfci.harvard.edu.
  • Matulonis UA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address: ursula_matulonis@dfci.harvard.edu.
  • Zhao JJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address: jean_zhao@dfci.harvard.ed
Cell Rep ; 25(11): 2972-2980.e5, 2018 12 11.
Article em En | MEDLINE | ID: mdl-30540933
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Proteína BRCA1 / Inibidores de Poli(ADP-Ribose) Polimerases / Imunidade / Proteínas de Membrana Limite: Animals / Female / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Proteína BRCA1 / Inibidores de Poli(ADP-Ribose) Polimerases / Imunidade / Proteínas de Membrana Limite: Animals / Female / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos