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An Open-Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM-080301 in Subjects with Advanced Hepatocellular Carcinoma.
El Dika, Imane; Lim, Ho Yeong; Yong, Wei Peng; Lin, Chia-Chi; Yoon, Jung-Hwan; Modiano, Manuel; Freilich, Bradley; Choi, Hye Jin; Chao, Tsu-Yi; Kelley, Robin K; Brown, Joanne; Knox, Jennifer; Ryoo, Baek-Yeol; Yau, Thomas; Abou-Alfa, Ghassan K.
Afiliação
  • El Dika I; Memorial Sloan Kettering Cancer Center, New York New York, USA.
  • Lim HY; Samsung Medical Center, Seoul, South Korea.
  • Yong WP; National University Hospital, Singapore.
  • Lin CC; National Taiwan University Hospital, Taipei, Taiwan.
  • Yoon JH; Seoul National University Hospital, Seoul, South Korea.
  • Modiano M; Arizona Oncology Associates, PC, Tucson, Arizona, USA.
  • Freilich B; Kansas City Research Institute, LLC, Kansas City, Missouri, USA.
  • Choi HJ; Severance Hospital, Yonsei University Health System, Seoul, South Korea.
  • Chao TY; Taipei Medical University, Shuang-Ho Hospital, Taipei, Taiwan.
  • Kelley RK; University of California, San Francisco, California, USA.
  • Brown J; Arbutus Biopharma, Inc., Warminster, Pennsylvania, USA.
  • Knox J; Princess Margaret Hospital, Toronto, Canada.
  • Ryoo BY; Asan Medical Center, Seoul, South Korea.
  • Yau T; Queen Mary Hospital, Hong Kong, People's Republic of China.
  • Abou-Alfa GK; Memorial Sloan Kettering Cancer Center, New York New York, USA abou-alg@mskcc.org.
Oncologist ; 24(6): 747-e218, 2019 06.
Article em En | MEDLINE | ID: mdl-30598500
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / RNA Interferente Pequeno / Nanopartículas / Lipídeos / Neoplasias Hepáticas / Antineoplásicos Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Oncologist Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / RNA Interferente Pequeno / Nanopartículas / Lipídeos / Neoplasias Hepáticas / Antineoplásicos Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Oncologist Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos