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Targeted delivery of nitric oxide via a 'bump-and-hole'-based enzyme-prodrug pair.
Hou, Jingli; Pan, Yiwa; Zhu, Dashuai; Fan, Yueyuan; Feng, Guowei; Wei, Yongzhen; Wang, He; Qin, Kang; Zhao, Tiechan; Yang, Qiang; Zhu, Yan; Che, Yongzhe; Liu, Yangping; Cheng, Jiansong; Kong, Deling; Wang, Peng George; Shen, Jie; Zhao, Qiang.
Afiliação
  • Hou J; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China.
  • Pan Y; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, PR China.
  • Zhu D; State key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Science, Nankai University, Tianjin, China.
  • Fan Y; School of Medicine, Nankai University, Tianjin, China.
  • Feng G; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China.
  • Wei Y; Department of Genitourinary Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
  • Wang H; State key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Science, Nankai University, Tianjin, China.
  • Qin K; State key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Science, Nankai University, Tianjin, China.
  • Zhao T; State key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Science, Nankai University, Tianjin, China.
  • Yang Q; Center for Research and Development of Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
  • Zhu Y; Spine Department, Tianjin Hospital, Tianjin, China.
  • Che Y; Center for Research and Development of Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
  • Liu Y; School of Medicine, Nankai University, Tianjin, China.
  • Cheng J; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, PR China.
  • Kong D; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China. jiansongcheng@nankai.edu.cn.
  • Wang PG; State key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Science, Nankai University, Tianjin, China.
  • Shen J; Department of Chemistry and Center for Therapeutics and Diagnostics, Georgia State University, Atlanta, GA, USA.
  • Zhao Q; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China. jieshen@nankai.edu.cn.
Nat Chem Biol ; 15(2): 151-160, 2019 02.
Article em En | MEDLINE | ID: mdl-30598545
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Óxido Nítrico Tipo de estudo: Guideline Limite: Animals Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Óxido Nítrico Tipo de estudo: Guideline Limite: Animals Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China