3,5-Disubstituted-indole-7-carboxamides as IKKß Inhibitors: Optimization of Oral Activity via the C3 Substituent.

Kerns, Jeffrey K; Busch-Petersen, Jakob; Fu, Wei; Boehm, Jeffrey C; Nie, Hong; Muratore, Michael; Bullion, Ann; Lin, Guoliang; Li, Huijie; Davis, Roderick; Lin, Xichen; Lakdawala, Ami S; Cousins, Rick; Field, Rita; Payne, Jeremy; Miller, David D; Bamborough, Paul; Christopher, John A; Baldwin, Ian; Osborn, Ruth R; Yonchuk, John; Webb, Edward; Rumsey, William L

Kerns, Jeffrey K; Busch-Petersen, Jakob; Fu, Wei; Boehm, Jeffrey C; Nie, Hong; Muratore, Michael; Bullion, Ann; Lin, Guoliang; Li, Huijie; Davis, Roderick; Lin, Xichen; Lakdawala, Ami S; Cousins, Rick; Field, Rita; Payne, Jeremy; Miller, David D; Bamborough, Paul; Christopher, John A; Baldwin, Ian; Osborn, Ruth R; Yonchuk, John; Webb, Edward; Rumsey, William L.

Afiliação

Kerns JK; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Busch-Petersen J; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Fu W; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Boehm JC; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Nie H; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Muratore M; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Bullion A; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Lin G; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Li H; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Davis R; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Lin X; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Lakdawala AS; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Cousins R; Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
Field R; Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
Payne J; Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
Miller DD; Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
Bamborough P; Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
Christopher JA; Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
Baldwin I; Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
Osborn RR; Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
Yonchuk J; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Webb E; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.
Rumsey WL; GlaxoSmithKline Inc., 709 Swedeland Road, King of Prussia Pennsylvania 19406, United States.

ACS Med Chem Lett ; 9(12): 1164-1169, 2018 Dec 13.

Article em En | MEDLINE | ID: mdl-30613320

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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